After you swallow CBD oil, what happens?
It might seem like your cells would start absorbing it right away, sending its goodness throughout your body. But pump the brakes — anything you consume has to be metabolized first.
During this metabolic process, sometimes called first pass metabolism or the first pass effect, the compounds in CBD oil are transformed into water-soluble compounds so the body can utilize and then excrete them. If this didn’t happen, those compounds would hang out in your body forever.
So the first pass effect is a natural and good thing, but it does have a downside: It reduces the potency of your cannabidiol (CBD).
The first pass effect is unique to CBD taken orally (like via tinctures or edibles), which can be quite the conundrum if you prefer these products. But there are ways around it — “first pass effect hacks,” if you will — that protect the potency of your CBD so you can enjoy max results.
Ready to earn your stripes as a first pass effect smarty pants hacker? Let’s go.
Understanding the first pass effect is important for CBD because it can affect the bioavailability of your CBD products. You could have the most primo, organic CBD oil around, but if your body is giving it a one-two punch after you take it — it won’t do you much good.
The concept of the first pass effect is simple.
This differs from inhalants, sublingual, and transdermal CBD, which enter the bloodstream before they reach the liver.
The first pass effect doesn’t only apply to CBD. It influences the absorption of pharmaceutical drugs and other substances, like alcohol, and the psychoactive cannabis compound THC.
It’s also a factor in why some people “feel” CBD and other drugs differently.(1) How your body metabolizes things is unique.
What’s really interesting is that first pass metabolism doesn’t always result in diminished potency. For alcohol, the metabolites produced in the process can actually be stronger and more toxic than the alcohol consumed.(2)
But when it comes to CBD, the first pass effect can make ingested products less effective.(3)
You’ll probably agree that weaker CBD isn’t a good thing. After all, you paid for a certain potency. So, how can you get around the first pass effect?
You have a few options, actually.
Since the first pass effect only applies to CBD you take orally, you could theoretically just not use oral CBD products.
However, this may not be a simple decision.
Inhalants, topical CBD, and transdermal CBD bypass the first pass effect, but every form of CBD has its pros and cons.
CBD gummies, tinctures, softgels, and edibles are essentials for those looking for holistic effects that last. That’s not something you can replicate with other forms of CBD.
You might have noticed that we didn’t mention one very popular delivery method: sublingual CBD. Let’s soak that one up now.
Some might categorize sublingual administration with oral administration because sublingual quite literally means “under the tongue.” This sounds like an oral method, but sublingual is actually its own thing.
You can bypass the first pass effect with sublingual absorption by holding CBD oil drops under your tongue before swallowing. But since you do ingest the rest, some of it will be subject to the first pass effect.
Think of sublingual absorption like an add-on to ingestion: Your mouth won’t fully absorb everything you drop under your tongue or spray in, but it will fast-track some of the CBD into your bloodstream.
Now, if only there were a way to help CBD you take orally bypass the first pass effect. Oh, wait — there is! Let’s learn about that.
If you’re thinking, “The only way you’re going to take my CBD edibles away from me is by prying them out of my cold, dead hands…but I also don’t want the first pass effect to ruin them.” — Nanotechnology is your best friend.
Nanotechnology makes particles of substances super duper tiny. So small, in fact, they can actually slip through the metabolic radar of your body. As a result, your CBD doesn’t get diluted after you take it. These full-strength nanoparticles allow up to a 90% absorption rate.
Your body is also able to absorb nano CBD faster than regular CBD, which is a win no matter what form of CBD you’re using.
CBD made with nanotechnology is called nano CBD.
At Pure Craft, we’ve worked with researchers at the Massachusetts Institute of Technology (MIT) to create the most effective CBD out there using nanotech. All of our CBD products are made with nano CBD, so you can enjoy them without worrying about the first pass effect.
Can’t get enough CBD hacks? Head toBiohacking With CBD For Optimal Wellness for more ways to optimize the effects of your CBD products.
Now you’re practically an expert on how to increase CBD absorption by avoiding the potency-ruining first pass effect!
Sure, you could pass on taking CBD orally, or use it sublingually..
But as you well know, nano CBD is the clear choice for getting the absolute most out of your CBD products, edible or otherwise. Why would you use anything else?
The great thing about the digital age is that it's opened up a whole world of opportunities for people who want to work from home. With a good in...Read More
Our phones are getting smarter and so are our supplements and CBD products. It makes sense — after years of bunk outcomes from old-school vitamins,...Read More
What could be better than filling your lungs with fresh air and watching the sunset while you enjoy a (fill in your favorite form of cannabis treat...Read More